In the eleventh annual Disruptor 50 list, CNBC highlights private companies that are chasing some of the market’s biggest opportunities, and growing despite a tough capital markets environment and slowing economy.

At least 35 are unicorns, with valuations of $1 billion or more – 12 are valued at over $10 billion. As many of the highest-flying start-ups have seen valuations pressured, this year’s list also identified many younger firms testing novel ideas earlier in their fundraising trajectories.  

Many of the Disruptor 50 companies have a social or environmental purpose that is core to their business model, including climate change, sustainable development, health care, financial inequities, and an inefficient global supply chain. 13 of this year’s Disruptors have a female founder. 14 feature CEOs from racial and ethnic minorities.  

The 50 companies selected using the proprietary Disruptor 50 methodology have raised over $54 billion in venture capital, according to PitchBook and company data, at an implied Disruptor 50 valuation of more than $362 billion.

1 OpenAI Believe the hype
2 Brex A better Silicon Valley banker
3 Canva A new face on graphic design
4 Relativity Space The first 3D-printed rocket takes off
5 Wiz Next-level cloud security
6 Alto Pharmacy Online Rx
7 Anduril Industries AI-powered defense
8 Octopus Energy Extending its climate tentacles
9 Lineage Logistics Improving links in the cold chain
10 Flexport The logistics industry’s cloud giant
11 Exotec A fleet of warehouse robots
12 Pivot Bio Sustainable fertilizer
13 Einride Heavy-duty EV trucking
14 Rippling Making waves across HR, IT and finance
15 Chime The branch-less future of the bank
16 Spring Health Mental benefits
17 Vanta Know your customer data
18 Discord Keeping the social media conversation (and controversies) going
19 Scale AI How the chatbots learn
20 Flock Freight Carbon-free trucking
21 Maven Clinic The new family practice
22 Arctic Wolf Always vigilant
23 Dedrone Aerial defense
24 Orca Security Killer cybersecurity in the cloud
25 Zipline 38 million autonomous miles flown
26 ElevateBio Scaling CRISPR
27 Tala Big in little loans
28 Stripe Making online pay
29 Ramp Automating the most annoying part of having a job
30 Guild On a new career path
31 Databricks Enterprise-level understanding
32 Notion Cutting through cloud clutter
33 ŌURA Wrapped around your finger
34 Mast Reforestation Wildfire fighter
35 BlocPower Climate-controlled cities
36 Cityblock Health Medicaid’s healthtech start-up
37 Evrnu Recycled trends
38 BeeHero The Pollinator
39 Phononic The brain in the cold chain
40 Snyk Making developers feel secure
41 GrubMarket Farm to table food tech
42 Airtable Speaking in low-code
43 Kindbody Family-building femtech
44 Cohere A Google-linked ChatGPT rival
45 Climeworks Carbon captured
46 Bowery Urban roots
47 Convoy Making trucks climate-connected
48 Sila The next silicon revolution
49 Monarch Tractor EV farming
50 SoLo Funds Lending, democratized

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